Link: http://www.av-comparatives.org
av-comparatives.org project reported the evaluation results of 16 leading AV products.
Proactive detection against 8,745 pieces of modified malware:
- 12 out of 16 products did not recognized even half of test pieces
- the best result is 58%
On-demand detection against 243,671 pieces of known malware:
- One vendor missed over 90,000 pieces of malware
- 4 out of 16 missed over 10,000 of pieces
So, in order to ensure that at least all known pieces of malware are detected you have to install dozens of AVs :-)
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